Research Posts

Professionalism and Medicine’s Social Contract with Society
Professionalism and Medicine's Social Contract with Society Medicine's relationship with society has been described as a social contract: an “as if” contract with obligations and expectations on the part of both society and medicine, “each of the other”. The term is often used without elaboration by those writing on professionalism in medicine. Based on the […]
Exercise-induced muscle damage on the contractile properties of the lumbar paraspinal muscles: a laser displacement mechanomyographic approach
Exercise-induced muscle damage on the contractile properties of the lumbar paraspinal muscles: a laser displacement mechanomyographic approach" MMG appears capable of detecting changes in muscle contractile properties associated with an acute bout of low back pain." #science #chiropractor #chiropractic #research #education #evidence based #patient centered #interprofessional #collaborative #rehabilitation #public health #spinal health #musculoskeletal health #ethics […]
It is time to move beyond ‘body region silos’ to manage musculoskeletal pain: five actions to change clinical practice
It is time to move beyond ‘body region silos’ to manage musculoskeletal pain: five actions to change clinical practice Current clinical research, education and practice commonly approaches musculoskeletal pain conditions in silos. A focus on body regions such as knee, hip, neck, shoulder and back pain as separate entities is manifest by region-specific clinical guidelines, […]
Functional Anatomy of the Spinal Cord
Functional Anatomy of the Spinal Cord" The spinal cord (SC) is the anatomical structure of the central nervous system (CNS) serving as a processing and relay station from and to the peripheral nerves. This cylinder of gray and white matter receives motor inputs from the brain and a wide range of sensory information from the rest […]
Clinical efficacy of platelet-rich plasma in the treatment of lateral epicondylitis: a systematic review and meta-analysis of randomized placebo-controlled clinical trials.
Clinical efficacy of platelet-rich plasma in the treatment of lateral epicondylitis: a systematic review and meta-analysis of randomized placebo-controlled clinical trials. To compare the effects of platelet-rich plasma (PRP) injection versus placebo (saline injection) on pain and joint function in lateral epicondylitis in randomized placebo-controlled trials. Randomized controlled trials that evaluated pain (visual analog scale […]
Visceral fat delivers signal to the brain that hurts cognition
Visceral fat delivers signal to the brain that hurts cognition Excessive weight around our middle gives our brain’s resident immune cells heavy exposure to a signal that turns them against us, setting in motion a crescendo of inflammation that damages cognition, scientists say. #science #chiropractor #chiropractic #research #education #evidence based #patient centered #interprofessional #collaborative #rehabilitation […]
Burden of Sciatica on US Medicare Recipients
Burden of Sciatica on US Medicare Recipients" The baseline cohort data of 1,000,952 patients yielded 250,869 patients (25%) who reported the diagnosis of sciatica, compared with 750,083 patients (75%) without sciatica. Patients with a history of sciatica tended to be younger, less educated, and notably with more medical comorbidities. Physical component summary outcomes were approximately […]
Passive Strategies for the Prevention of Muscle Wasting During Recovery from Sports Injuries
Passive Strategies for the Prevention of Muscle Wasting During Recovery from Sports Injuries"The concomitant application of BFR and low-intensity exercise has shown promising results in the prevention of disuse-induced muscle atrophy. Some benefits might also be obtained with BFR alone (i.e., with no exercise), but evidence is still inconclusive. NMES, which can be applied both […]
Neuropathic Pain Causes Memory Deficits and Dendrite Tree Morphology Changes in Mouse Hippocampus
Neuropathic Pain Causes Memory Deficits and Dendrite Tree Morphology Changes in Mouse Hippocampus Thus, we found that pain information entering the hippocampus causes neuroplastic changes. The abnormalities in neurite arborization, dendritic length and dendritic spines morphology are observed within the hippocampal regions involved in the processing of pain information. Moreover, changes in the dendrite morphology […]
Intraoperative Ischemic Stroke in Elective Spine Surgery: A Retrospective Study of Incidence and Risk
Intraoperative Ischemic Stroke in Elective Spine Surgery: A Retrospective Study of Incidence and Risk With the increase of spinal procedures, it is important to identify patients at risk for having an ischemic stroke and to optimize their comorbidities preoperatively. Patients with intraoperative ischemic stroke carry a higher risk for morbidity and mortality during the index […]
To Flex or Not to Flex? Is There a Relationship Between Lumbar Spine Flexion During Lifting and Low Back Pain? A Systematic Review With Meta-analysis
To Flex or Not to Flex? Is There a Relationship Between Lumbar Spine Flexion During Lifting and Low Back Pain? A Systematic Review With Meta-analysis There was low-quality evidence that greater lumbar spine flexion during lifting was not a risk factor for LBP onset/persistence or a differentiator of people with and without LBP. J Orthop […]
Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review
Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review On the basis of the available literature, there is some evidence that plant-based dietary patterns such as vegetarian and vegan diets might have pain-relieving effects on chronic musculoskeletal pain. This effect might arise from the anti-inflammatory characteristics of the plant-based dietary patterns, but studies […]
Effect of changes in the lumbar posture in lifting on trunk muscle and spinal loads: A combined in vivo, musculoskeletal, and finite element model study
Effect of changes in the lumbar posture in lifting on trunk muscle and spinal loads: A combined in vivo, musculoskeletal, and finite element model study Collectively and with due consideration of the risk of fatigue and viscoelastic creep especially under repetitive lifts, current results support a free posture (in between the extreme kyphotic and lordotic […]
Central nervous system contribution to mechanically produced motor and sensory responses
Central nervous system contribution to mechanically produced motor and sensory responses Peripheral tissue pathology causes a rapid and enduring increase in the excitability of spinal cord neurones. This review examines some of the basic and clinical research which suggests that the central nervous system is capable of making a contribution to clinical signs and symptoms. […]
US Health Care Spending by Payer and Health Condition, 1996-2016
US Health Care Spending by Payer and Health Condition, 1996-2016 Estimates of US spending on health care showed substantial increases from 1996 through 2016, with the highest increases in population-adjusted spending by public insurance. Although spending on low back and neck pain, other musculoskeletal disorders, and diabetes accounted for the highest amounts of spending, the […]
Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials
Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials The reporting quality of the included studies was assessed based on the Cochrane Collaboration’s tool for assessing the risk of bias in randomized trials and integrated together with studies that investigated the same subjects. The included studies that examined the improvement of […]
Eliciting the Patient’s Agenda- Secondary Analysis of Recorded Clinical Encounters
Eliciting the Patient’s Agenda- Secondary Analysis of Recorded Clinical Encounters Clinicians seldom elicit the patient’s agenda; when they do, they interrupt patients sooner than previously reported. Physicians in specialty care elicited the patient’s agenda less often compared to physicians in primary care. Failure to elicit the patient’s agenda reduces the chance that clinicians will orient […]
Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines)
Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines) Placebo comparisons are increasingly being considered for randomised trials assessing the efficacy of surgical interventions. The aim of this Review is to provide a summary of knowledge on placebo controls in surgical trials. A placebo control is a complex type of comparison group in […]
Investigation of a possible association of potentially inappropriate medication for older adults and frailty in a prospective cohort study from Germany
Investigation of a possible association of potentially inappropriate medication for older adults and frailty in a prospective cohort study from Germany The association of PIM use and frailty seems to be restricted to drug classes, which can induce frailty symptoms (anticholinergics, benzodiazepines, z-substances and antipsychotics). Physicians are advised to perform frailty assessments before and after […]
Impact of Chiropractic Care on Use of Prescription Opioids in Patients with Spinal Pain
Impact of Chiropractic Care on Use of Prescription Opioids in Patients with Spinal Pain Patients with spinal pain who saw a chiropractor had half the risk of filling an opioid prescription. Among those who saw a chiropractor within 30 days of diagnosis, the reduction in risk was greater as compared with those with their first visit […]
Original Research Less Than Half of Patients Recover Within 2 Weeks of Injury After a Sports-Related Mild Traumatic Brain Injury A 2-Year Prospective Study
Original Research Less Than Half of Patients Recover Within 2 Weeks of Injury After a Sports-Related Mild Traumatic Brain Injury: A 2 year Prospective Study This study challenges current perceptions that most people with a SR-mTBI (concussion) recover within 10 to 14 days and that age is a determinant of recovery rate. Active rehabilitation results […]
Baseline Characteristics May Help Indicate the Best Choice of Health Care Provider for Back Pain Patients in Primary Care: Results From a Prospective Cohort Study
Baseline Characteristics May Help Indicate the Best Choice of Health Care Provider for Back Pain Patients in Primary Care: Results From a Prospective Cohort Study Most of the investigated prognostic factors for developing persistent pain and disability were more strongly associated with outcomes in the GP setting compared with the chiropractic setting. For 5 factors […]
Moving towards a contemporary chiropractic professional identity
Moving towards a contemporary chiropractic professional identity Whilst these three main chiropractic identity subtypes exist, within the literature the terminology used to describe them differs. Research aimed at categorising the chiropractic profession identity into exclusive subtypes found that at least 20% of chiropractors have an exclusive vertebral subluxation focus. However, deeper exploration of the literature […]
Comparison of common interventions for the treatment of infantile colic: a systematic review of reviews and guidelines
Comparison of common interventions for the treatment of infantile colic: a systematic review of reviews and guidelines The strongest evidence for the treatment of colic was probiotics for breastfed infants, followed by weaker but favourable evidence for manual therapy indicated by crying time. Both forms of treatment carried a low risk of serious adverse events. […]
Shock wave therapy for rotator cuff disease with or without calcification
Shock wave therapy for rotator cuff disease with or without calcification In people with rotator cuff disease, moderate-certainty evidence (downgraded due to bias) shows that shock wave therapy probably does not improve pain and function compared with placebo, and low-certainty evidence (downgraded due to bias and lack of accuracy) shows there may be no improvement […]
Research Culture: Framework for advancing rigorous research
Research Culture: Framework for advancing rigorous research There is a pressing need to increase the rigor of research in the life and biomedical sciences. To address this issue, we propose that communities of 'rigor champions' be established to campaign for reforms of the research culture that has led to shortcomings in rigor. These communities of […]
Characterizing the Mechanical Properties of Ectopic Axonal Receptive Fields in Inflamed Nerves and Following Axonal Transport Disruption
Characterizing the Mechanical Properties of Ectopic Axonal Receptive Fields in Inflamed Nerves and Following Axonal Transport Disruption In this study, we have characterised the mechanical properties of the ectopic axonal receptive fields in the rat and have examined the contribution of mechanically sensitive ion channels to the development of AMS following neuritis and vinblastine-induced axonal […]
Intermittent Energy Restriction Attenuates the Loss of Fat Free Mass in Resistance Trained Individuals. A Randomized Controlled Trial
Intermittent Energy Restriction Attenuates the Loss of Fat Free Mass in Resistance Trained Individuals. A Randomized Controlled Trial There is a lack of research into how lean, resistance trained (RT) individuals respond to intermittent energy restricted diets. Therefore, we investigated body composition changes in RT-individuals during continuous energy restriction or intermittent restriction. #science #chiropractor #chiropractic […]
Life satisfaction and musculoskeletal complaints in a population seeking osteopathy care: consecutive sample of 611 patients
Life satisfaction and musculoskeletal complaints in a population seeking osteopathy care: consecutive sample of 611 patients Our study suggests that the mean life satisfaction of those presenting for musculoskeletal care at an osteopathy student-led clinic is slightly higher than the American population – the available reference population for the measures used. This study is also […]
Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the consumption of major foods […]