Neuropathic Pain Causes Memory Deficits and Dendrite Tree Morphology Changes in Mouse Hippocampus Thus, we found that pain information entering the hippocampus causes neuroplastic changes. The abnormalities in neurite arborization, dendritic length and dendritic spines morphology are observed within the hippocampal regions involved in the processing of pain information. Moreover, changes in the dendrite morphology within the hippocampal subregions are different due to the anatomical and functional heterogeneity of the hippocampus. The detailed mechanisms of the revealed morphological changes are yet to be studied. However, it is clear that the key role is played by the Arс protein, participating in glutamatergic transmission and providing a link between synaptic activity and the structural-functional plasticity of neurons.
#science #chiropractor #chiropractic #research #education #evidence based #patient centered #interprofessional #collaborative #rehabilitation #public health #spinal health #musculoskeletal health #ethics #pain #function #disability #QOL #knowledgetranslation
