"In covariate-adjusted linear regression models for total hip, femoral neck, spine and whole body BMD, women sleeping 5 hours or less per night had BMD values that were approximately 0.015, 0.012, 0.018, and 0.018 g/cm2 lower compared with women who slept 7 hours per night (reference group; Table 2). {TBL 2} The spine and whole body BMD values were also lower on average for women who slept 6 hours per night, for a difference of approximately 0.01 g/cm2 compared with women sleeping 7 hours/night.In multinomial logistic models, women sleeping 5 hours or less per night had significantly higher odds of low bone mass of the total hip and whole body compared with women sleeping 7 hours per night; hip and total body odds ratios (ORs) were 1.22 and 1.37, respectively (Table 3). {TBL 3} Similarly, women sleeping 5 hours or less per night had higher odds of osteoporosis of the total hip, spine, and whole body; ORs were 1.63, 1.28, and 1.94, respectively. Women sleeping 6 hours per night had higher but slightly attenuated odds of spine and whole body osteoporosis (versus 7 hours per night), with ORs of 1.17 and 1.27, respectively. For femoral neck BMD, we failed to observe statistically significant associations with low bone mass or osteoporosis and sleep duration."
Short Sleep Is Associated With Low Bone Mineral Density and Osteoporosis in the Women's Health Initiative
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