Treatment of Low Back Pain This guideline provides a pragmatic approach to treating LBP stratified by symptom duration. Among the many noninvasive treatments considered, no option shows a large benefit for pain and back-specific function. Even less can be said of therapeutic effects on other clinical outcomes like reduction in disability and improvement in quality of life. Because acetaminophen is no longer recommended for treatment of acute or subacute LBP, the only potentially effective pharmacologic agents are NSAIDs and skeletal muscle relaxants. Opioids offer moderate short-term benefit for chronic LBP, but the guideline cautions against their use.
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