What level of inflammation leads to structural damage in the sacroiliac joints? A Four-Year Magnetic Resonance Imaging Follow-up Study of Low Back Pain Patients While extensive SI joint BME was a strong independent predictor of development of structural lesions, limited and intermediate BME were mostly transient and only rarely evolved into extensive BME or structural lesions. These findings enhance our understanding of the natural development of SI joint lesions and indicate different progression patterns for limited/intermediate versus extensive BME, possibly due to different etiologies.
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